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毛囊型职业性黑变病1例
引用本文:曾雪,吴小红,王煜明,丁旭. 毛囊型职业性黑变病1例[J]. 中国皮肤性病学杂志, 2012, 26(5): 430-431
作者姓名:曾雪  吴小红  王煜明  丁旭
作者单位:中国中医科学院广安门医院皮肤科,北京,100053
摘    要:
患者男,47岁。双上肢、躯干出现黑色斑点3年余,与毛囊分布区一致。患者从事汽车维修工作,长期接触固化剂。皮损组织病理示:表皮角化过度,毛囊角栓,基底细胞液化变性累及毛囊基底膜带,形成毛囊周围裂隙,真皮浅层较多噬色素细胞,毛细血管周围及毛囊附属器周围有较多淋巴细胞、组织细胞浸润。诊断:职业性黑变病。

关 键 词:职业性黑变病  毛囊

A Case of Occupational Melafism
ZENG Xue , WU Xiao-hong , WANG Yu-ming , DING Xu. A Case of Occupational Melafism[J]. The Chinese Journal of Dermatovenereology, 2012, 26(5): 430-431
Authors:ZENG Xue    WU Xiao-hong    WANG Yu-ming    DING Xu
Affiliation:(Department of Dermatology,Guang’anmen Hospital,Chinese Academy of Traditional Chinese Medicine,Beijing 100053,China)
Abstract:
A 47-year-old male was found with a lot of black spots on upper arms and trunk area three years ago. These lesions gradually increased. He has been engaging in automobile maintenance and touching the hardener for long time. Biopsy revealed hyperkeratosis with follicular plug and liquefaction degeneration of basal cells with perifollicular cleft formation,a bulk of lymphocytes infiltrated in appendages and blood vessels of the dermis. He was diagnosed with Occupational Melanism and then treated by Vitamin C 300 mg per day. So far,he has been in the follow-up for 1 month.
Keywords:Occupational melanism  Folliculus
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