麝香保心丸联合替格瑞洛治疗冠心病心绞痛的临床研究

目的 探究麝香保心丸联合替格瑞洛片治疗冠心病心绞痛的临床疗效.方法 选择2019年11月—2021年2月在济源市人民医院就诊治疗的102例冠心病心绞痛患者,按照入院先后顺序将所有患者分为对照组和治疗组,每组各51例.对照组口服替格瑞洛片,90 mg/次,2次/d.治疗组在对照组的基础上口服麝香保心丸,45 mg/次,3...

Clinical study on Shexiang Baoxin Pills combined with ticagrelor in treatment of angina pectoris of coronary heart disease

Objective To explore the clinical study of Shexiang Baoxin Pills combined with Ticagrelor Tablets in treatment of angina pectoris of coronary heart disease.Methods Patients (102 cases) with angina pectoris of coronary heart disease in Jiyuan Shi People''s Hospital from November 2019 to February 2021 were randomly divided into control and treatment groups, and each group had 51 cases. Patients in the control group were po administered with Ticagrelor Tablets, 90 mg/time, twice daily. Patients in the treatment group were po administered with Shexiang Baoxin Pills on the basis of the control group, 45 mg/time, three times daily. Patients in two groups were treated for 2 months. After treatment, the clinical efficacies of angina pectoris and ECG were evaluated, and the attack status of angina pectoris, cardiac functions, and serum inflammatory factors in two groups were compared.Results After treatment, the total effective rates of angina pectoris and ECG in the treatment group were higher than those in the control group, and there was a difference between the groups (P < 0.05). After treatment, the attack frequency and duration of two groups were significantly lower than those of the control group (P < 0.05), and the attack frequency and duration of the treatment group were significantly improved than those of the control group (P < 0.05). After treatment, the LVEF of two groups were significantly decreased, but the CO and SV of two groups were significantly increased, and there was a significant difference in the same group (P < 0.05). The LVEF of the treatment group was significantly lower than that of the control group, but the CO and SV of the treatment group were significantly higher than those of the control group (P < 0.05). After treatment, the levels of IL-6, Hcy, and IMA in two groups were significantly decreased, and there was a significant difference in the same group (P < 0.05). And the levels of IL-6, Hcy, and IMA in the treatment group were significantly lower than those in the control group (P < 0.05).Conclusion Shexiang Baoxin Pills combined with Ticagrelor Tablets has curative effect in treatment of angina pectoris of coronary heart disease, can improve patients'' clinical symptoms, improve patients'' cardiac function, and reduce inflammatory reaction, with good safety, which has a certain clinical application value.