脑深部电刺激术治疗帕金森病的进展与展望

脑深部电刺激术(deep brain stimulation,DBS)目前已成为国内外认可的帕金森病重要治疗方案。随着脑科学、手术方法、磁共振成像技术的不断发展,以及大量临床循证医学证据的逐渐完善,DBS治疗帕金森病在手术时机、靶点选择、症状控制、治疗机制、设备改进等方面均取得了较大的进展。但是,其在中轴运动症状和非运动症状的控制方面尚存在一些不足,设备、程控设置等方面也有待改进。

Progress and prospect of deep brain stimulation for Parkinson

Deep brain stimulation (DBS) has become an important treatment for Parkinson disease (PD) in domestic and abroad. With continuous developments of brain science, surgical methods, MRI technology, and gradual improvement of evidence-based medicine factors, significant progresses have been achieved in timing of operation, target selection, symptom control, treatment mechanism and equipment improvement for DBS in treating PD. However, there are some inadequacies in controlling axial motor symptoms and non-motor symptoms, and the equipment and programmer also need to improve.