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In vitro modeling of nonhypoxic cold ischemia-reperfusion simulating lung transplantation |
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| Authors: | Monica Casiraghi Jason R. Tatreau John B. Abano John W. Blackwell Larry Watson Keith Burridge Scott H. Randell Thomas M. Egan |
| Affiliation: | a Division of Cardiothoracic Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC b Department of Thoracic Surgery, Division of Thoracic Surgery, European Institute of Oncology, Milan, Italy c Cystic Fibrosis/Pulmonary Research and Treatment Center and the Division of Pulmonary and Critical Care Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC d Department of Cell and Developmental Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC |
| Abstract: | |
| Keywords: | AM, alveolar macrophage BOS, bronchiolitis obliterans syndrome ERK, extracellular signal-regulated kinase HMVEC, human pulmonary microvascular endothelial cell HUVEC, human umbilical vein endothelial cell IκBα, inhibitor of nuclear factor κB,α IL, interleukin IRI, ischemia-reperfusion injury JNK, Janus kinase LDH, lactate dehydrogenase LTX, lung transplantation MAPK, mitogen-activated protein kinase NF, nuclear factor PBS, phosphate-buffered saline TLR, Toll-like receptor |
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