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老年男性骨密度与脂质过氧化相关性研究
引用本文:赵玉堂 于万良 杨剑辉 尹秋霞 李金花. 老年男性骨密度与脂质过氧化相关性研究[J]. 中国骨质疏松杂志, 1997, 3(4): 28-29
作者姓名:赵玉堂 于万良 杨剑辉 尹秋霞 李金花
作者单位:济南军区总医院骨矿研究室
摘    要:
对98例男性老年人的骨密度、血清超氧化物歧化酶(SOD)、过氧化脂质(LPO)、丙二醛(MDA)、谷光甘肽(GSH)进行测定,旨在研究老年人骨密度值变化与衰老的关系。结果:老年人BMD、SOD、GSH随年龄增长逐渐减少,BMD与SOD、GSH水平呈正相关,与LPO、MDA水平呈负相关。表明老年人骨密度与其衰老生化指标呈显著相关。老年人骨密度的丢失可作为衰老的重要指标之一。

关 键 词:骨密度,脂质过氧化

Correlation between bone mineral content and lipid peroxidation in male elderly
Zhao Yutang,Yu Wanliang,Yang Jianhui,Ying Qiuxia and Li Jinghua. Correlation between bone mineral content and lipid peroxidation in male elderly[J]. Chinese Journal of Osteoporosis, 1997, 3(4): 28-29
Authors:Zhao Yutang  Yu Wanliang  Yang Jianhui  Ying Qiuxia  Li Jinghua
Abstract:
98 healthy males aged over 60 were recruited for determination of bone mineral content, serum superoxide dismutase (SOD),lipid peroxide (LPO), MDA and glutathione peroxidase (GSH) in order to find the possible relationship between senescence and these markers. The results showed that BMD,SOD and GSH decreased with the increase of age. BMD was positively relative to SOD and GSH,but negatively relative to LPO and MDA. Loss of BMD might be a criterion for diagnosis of senescence.
Keywords::Bone mineral content Lipid peroxidation  
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