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| 绝经后骨质疏松患者的骨特异性碱性磷酸酶变化及其临床意义 | |
| 引用本文： | 胡国亮 翁建平. 绝经后骨质疏松患者的骨特异性碱性磷酸酶变化及其临床意义[J]. 中国骨质疏松杂志, 1997, 3(4): 15-16 |
| 作者姓名： | 胡国亮 翁建平 |
| 作者单位： | 中山医科大学附属第一医院内分泌科 |
| 摘 要： | 为了解骨形成的变化在绝经后骨质疏松发病中的作用，本文测定３７例绝经后骨质疏松患者和３１例健康绝经后妇女的骨特异性碱性磷酸酶，分析了这一变化与血总碱性磷酸酶及骨密度（用双能Ｘ线吸收仪测定）的相关性。结果发现绝经后骨质疏松患者骨特异性碱性磷酸酶和骨钙素较对照组明显降低，但这一变化与骨密度值无明显的相关性。提示骨形成减低并非绝经后骨质疏松的主要发病机理。 |
| 关 键 词： | 骨质疏松症，骨特异性碱性磷酸酶，骨密度，碱性磷酸酶，双能X线吸收仪 |
Changes of serum bone specific alkaline phosphatase in patients with postmenopausal osteoporosis |
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| Hu Guolang and Weng Jianping. Changes of serum bone specific alkaline phosphatase in patients with postmenopausal osteoporosis[J]. Chinese Journal of Osteoporosis, 1997, 3(4): 15-16 | |
| Authors: | Hu Guolang and Weng Jianping |
| Abstract: | To know the changes of serum bone specific alkaline phosphatase and its role in the pathogenesis of postmenopausal osteoporosis (POP), 37 cases of POP and 31 healthy postmenopausal women were researched. Bone mineral density (BMD ), serum bone specific alkaline phosphatates (BAI.P), total alkaline phosphatase (TALP) and osteocalcine were assayed. The results suggest that there is no correlation between decreased BALP and osteocalcine levels with BMD. Low bone formation may play minor role in the pathogenesis of POP. |
| Keywords: | Osteoporosis Bone mineral density Alkaline phosphatase Dual energy Xray absorptiometry |
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