| Abstract: | ![]()
A comparative cytological study was made of the control and regenerating liver in two strains of rats: August and cotton-tail. Two-thirds of the liver was removed from both groups of experimental animals and the intact organ served as the control. The animals were killed five or six at a time 30 h and 3, 8, 42, and 120 days after partial hepatectomy. The number of binuclear cells, the dimensions of the mononuclear hepatocytes and of their nuclei, and the mitotic activity and ploidy of the cells were studied. With the exception of mitotic activity, the regenerating and intact liver of the August rats differed from the regenerating and intact liver of the cotton-tail rats in all the above-mentioned cytological parameters. It is concluded that differences in the cytological parameters between the two different strains are due to the genotype of the particular strain.Laboratory of Growth and Development, Institute of Human Morphology, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR A. P. Avtsyn.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 82, No. 8, pp. 987–989, August, 1976. |
