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1株携带6种β-内酰胺酶基因的肺炎克雷伯菌
引用本文:周军,王智刚,史伟峰. 1株携带6种β-内酰胺酶基因的肺炎克雷伯菌[J]. 中华医院感染学杂志, 2007, 17(9): 1076-1078
作者姓名:周军  王智刚  史伟峰
作者单位:苏州大学附属第三医院,江苏,常州,213003
摘    要:目的了解对亚胺培南敏感的肺炎克雷伯菌(KPN)β-内酰胺酶产生状况。方法对1株KPN用PCR法进行了16种β-内酰胺酶基因(TEM、SHV、LEN、OKP、CTX-M-1群、CTX-M-2群、CTX-M-9群、OXA-1群、OXA-2群、OXA-10群、PER、GES、VEB、CARB、DHA、ACT-1)检测。结果检测显示TEM、SHV、CTX-M-1群、CTX-M-9群、OXA-1群、DHA等6种阳性。结论该株KPN同时携带6种β-内酰胺酶基因。

关 键 词:肺炎克雷伯菌  β-内酰胺酶  基因
文章编号:1005-4529(2007)09-1076-03
收稿时间:2007-01-12
修稿时间:2007-03-16

Discovery of a Klebsiella pneumoniae Strain Carrying Six Kinds of Beta-lactamase Genes
ZHOU Jun,WANG Zhi-gang,SHI Wei-feng. Discovery of a Klebsiella pneumoniae Strain Carrying Six Kinds of Beta-lactamase Genes[J]. Chinese Journal of Nosocomiology, 2007, 17(9): 1076-1078
Authors:ZHOU Jun  WANG Zhi-gang  SHI Wei-feng
Affiliation:The Third Affiliated Hospital, Soochow University, Changzhou, Jiangsu 213003, China
Abstract:OBJECTIVE To investigate the generation of beta-lactamases from Klebsiella pneumoniae(KPN) which is only susceptible to imipenem.METHODS Sixteen kinds of beta-lactamase genes were detected in a KPN strain by PCR.The genes included TEM,SHV,LEN,OKP, CTX-M-1 group,CTX-M-2 group,CTX-M-9 group,OXA-1 group,OXA-2 group,OXA-10 group,PER,GES,VEB,CARB,DHA,and ACT-1.RESULTS The assay showed six positive genes including TEM,SHV,CTX-M-1 group,CTX-M-9 group,OXA-1 group,and DHA.CONCLUSIONS The KPN strain carries six kinds of beta-lactamase genes simultaneously.
Keywords:Klebsiella pneumoniae   Beta-lactamase   Gene
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