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Suppression of temperature sensitive mutations in oncogene-related CDC genes in Saccharomyces cerevisiae by catabolite repression resistance and cytoplasmic petite mutations
Authors:V. Egilsson  V. Gudnason  A. Jonasdottir  V. Andresdottir
Affiliation:(1) Laboratory of Cell Biology, The University Hospital of Iceland, 105 Reykjavik, Iceland
Abstract:
Summary The ldquostartrdquo cell division control genes CDC36 and CDC28 have been reported to contain a certain sequence homology to tissue oncogenes (ets and some protein kinase encoding oncogenes respectively). Here we report that temperature sensitive mutations in these genes are suppressed in cytoplasmic ldquopetiterdquo mutants and catabolite repression resistant mutants.
Keywords:Yeast  Carbon catabolite repression  Oncogene-related genes
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