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Paediatric germ cell tumours and congenital abnormalities: a Children's Oncology Group study |
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| Authors: | K J Johnson J A Ross J N Poynter A M Linabery L L Robison X O Shu |
| Affiliation: | 1.Division of Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA;2.Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA;3.Department of Epidemiology and Cancer Control, St Jude Children''s Research Hospital, Memphis, TN 37232, USA;4.Department of Medicine, Vanderbilt Ingram-Cancer Center and Center for Health Services Research, Vanderbilt University, Nashville, TN 38105, USA |
| Abstract: | Methods:Maternally reported congenital abnormalities (CAs) were examined in a case–control study of 278 cases of paediatric germ cell tumours (GCTs) and 423 controls.Results and conclusionsGerm cell tumours were significantly associated with cryptorchidism in males (OR=10.8, 95% CI: 2.1–55.1), but not with any other specific CA in either sex. |
| Keywords: | germ cell tumours paediatrics congenital abnormalities |