原发性乳腺鳞状细胞癌的临床分析

目的 探讨乳腺鳞状细胞癌的临床病理学特点和诊断治疗方法。方法 回顾性分析7例经手术和病理证实乳腺鳞状细胞癌临床表现,手术和病理资料。结果 本组患者5例表现无痛性肿块,2例伴局部疼痛。肿块细针穿刺均找到癌细胞。5例行根治术,2例行改良术。病理报告：乳腺浸润性鳞状细胞癌,1例出现腋窝淋巴结转移。4例获得随访,其中2例健在,2例死亡;3例失访。结论 乳腺鳞状细胞癌确诊依靠病理学检查,手术(改良术、根治术)是最有效的治疗方法,术后需辅以放化疗。

Clinical analysis of primary squamous cell carcinoma of the breast

Objective To study the clinicopathological features of primary squamous cell carcinoma(SCC) of breast and the diagnosis and treatment of the disease. Methods The clinical, operative and pathological data from 7 cases of SCC of breast were retrospectively analysed. Results Five patients complained of painless mass and two of them were accompanied with local pain. All patients were diagnosed as having SCC by fine-needle aspiration before operation. Two patients underwent modified radical mastectomy, and the others received radical mastectomy. Pathological examination showed primary squamous cell carcinoma of the breast with metastasis to axlliary lymph nodes in one patient. Follow-up of four paients revealed that two patients are living well and two paients died. Three patients lost to follow up. Conclusion The diagnosis of primary squamous cell carcinoma of the breast is dependent on pathological results. Radical mastectomy including modified radical mastectomy is most effective in the treatment of mammary SCC. Postoperative chemotherapy and radiaion are necessary auxiliary therapy.