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28例脑转移瘤放射治疗疗效分析
引用本文:王牧民,黄静,娄云峰. 28例脑转移瘤放射治疗疗效分析[J]. 现代肿瘤医学, 2007, 15(8): 1080-1081
作者姓名:王牧民  黄静  娄云峰
作者单位:洛阳市中心医院放疗科,河南,洛阳,471000
摘    要:目的:探讨脑转移瘤放疗疗效及预后因素。方法:从2000年5月~2002年5月对28例脑转移瘤进行放射治疗。采用6MV-X线,两侧平行相对野作全脑照射,(1.8~2)Gy/次,(36~40)Gy后缩野针对转移灶加量(14~20)Gy。结果:影像学有效率64.3%。中位生存期5.6个月,6个月生存率46.4%,1年生存率21.4%。结论:影响预后的因素主要有:KPS评分、脑转移数目、颅外有无转移和原发灶是否控制。

关 键 词:脑转移瘤  放射治疗  预后因素
文章编号:1672-4992-(2007)08-1080-02
修稿时间:2006-10-12

Anal ysis of radiotherapy effect and prognostic factors in brain metastase
WANG Mu-min,HUANG Jing,LOU Yun-feng. Anal ysis of radiotherapy effect and prognostic factors in brain metastase[J]. Journal of Modern Oncology, 2007, 15(8): 1080-1081
Authors:WANG Mu-min  HUANG Jing  LOU Yun-feng
Affiliation:Department of Radiation Oncology ,Luoyang Central Hospital , Henan 471000 China.
Abstract:Objective:To study the effect of radiotherapy and prognostic factors in metastatic brain tumor.Methods:From May 2000 to May 2002,28 cases of brain metastatic tumor received radiotherapy.In all cases,radiotherapy was administered 5 days/week by means of 6-MV photons from a linear accelerator.Patients received the whole brain radiation therapy(WBRT) with a dose of(36~40)Gy followed by a local boost dose of radiation of(14~20)Gy.Results:The response rate was 64.3%.Overall median survival time was 5.6 months.The 6-month survival rate and one-year survival rate were 46.4% and 21.4% respectively.Conclusion:Karnofsky performance status(KPS),number of brain metastase,primary tumor status and extracranial metastases are prognostic factors in patients with brain tumor metastases.
Keywords:brain metastases  radiotherapy  prognostic factors
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