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The effect of fibromyalgia treatment on tinnitus
Affiliation:1. Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Centre “Sestre milosrdnice”, Vinogradska 29, 10000 Zagreb, Croatia;2. School of Medicine, University of Zagreb, Šalata 2b, 10000 Zagreb, Croatia
Abstract:ObjectivesWe investigated the frequency of tinnitus in fibromyalgia patients and the effect of drugs used for routine fibromyalgia on tinnitus.MethodsWe included 101 diagnosed fibromyalgia patients. After detailed ear nose throat examination, audiometric tests and tinnitus handicap index (THI) were performed. After the tests, routine treatment for fibromyalgia was started by the physical therapy and rehabilitation department. Two months after the beginning of the treatment, THI were repeated again and the results were statistically evaluated.ResultsAll patients included in the study were women. 74.3% of the patients had tinnitus. Pregabalin and selective serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant-treated patients were evaluated; In both groups, there was a statistically significant difference between pre- and post-treatment tinnitus levels (p < .001). However, there was no statistically significant difference between pregabalin group and diloxetine group according to treatment results.ConclusionsThe incidence of tinnitus is high in fibromyalgia patients. That pregabalin and duloxetine agents routinely used in fibromyalgia require further experimental and human studies in order to be able to use in tinnitus.
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