甲状腺术后患者发生恶心呕吐综合征的影响因素分析

目的探讨甲状腺术后患者发生恶心呕吐综合征(symdrome of postoperative nausea and vomiting,SPNV)影响因素。方法对214例行甲状腺手术患者资料进行回顾性分析,了解患者SPNV发生及影响因素情况。结果术后发生SPNV72例,发生率为33.64%;其中恶心发生率为100.00%,1度、2度、3度分别占47.22%、27.78%、25.00%;呕吐发生率为38.89%,轻度、中度、重度分别占32.14%、57.14%、10.71%;患者不同性别、吸烟史、麻醉方式与手术时间与患者术后发生SPNV具有相关性(均P0.05);多因素分析结果显示,患者为女性、全麻麻醉方式、手术时间≥2 h是引起患者术后发生SPNV的独立危险因素(均P0.05)。结论甲状腺手术患者术后SPNV发生率较高,女性、全麻麻醉方式及手术时间长是引起患者发生SPNV的独立危险因素。

Risk factors of nausea and vomiting syndrome after thyroidectomy

Objective To investigate the risk factors of nausea and vomiting syndrome after thyroidectomy. Method The clinical data of 214 patients undergoing thyroidectomy were analyzed retrospectively to look into the risk factors. Results Seventy-two patients contracted nausea and vomiting syndrome after thyroidectomy, with an incidence of 33.64%. All of them had nausea of degrees 1, 2 and 3, taking up 47.22%, 27.78% and 25.00%, respectively. 38.89% of them had vomiting of mild, intermediate and severe degrees, accounting for 32.14%, 57.14% and 10.71%, respectively. Gender, smoking history, anesthesia and surgical duration were correlated with the syndrome （All P 〈 0.05）. Non-conditional Logistic regression analysis showed that female, general anesthesia, operative duration I〉 2h were independent risk factors （all P 〈 0.05）. Conclusions Syndrome of nausea and vomiting after hyroidectomy has a higher incidence. Female, general anesthesia and surgical duration are independent risk factors. Interventional measures pertinent to these factors may reduce the incidence of nausea and vomiting syndrome after thyroidectomy.