直肠癌新辅助化疗病理完全缓解1例并文献复习

【摘要】〓目的〓探讨进展期结直肠癌新辅助化疗的临床疗效。方法〓报道中山大学孙逸仙纪念医院胃肠外科收治的1例接受新辅助化疗的进展期直肠癌患者的诊疗经过,并复习相关文献。 结果〓经过3疗程的新辅助化疗,患者术后病理结果提示完全病理缓解(pCR)。结论〓新辅助化疗对进展期结直肠癌患者是有效的,适合在进展期结直肠癌患者术前应用。

One case report of pathological complete remission of rectal cancer after neoadjuvant chemotherapy and review of literature

Objective To explore the clinical efficacy of neoadjuvant chemotherapy for patients with colorectal cancer. Methods The diagnosis and treatment course of one case with advanced rectal cancer undergoing neoadjnvant chemotherapy in the Gastroenterology Department, Sun Yat-sen Memorial Hospital of Sun Yat-sen University was reported, and related literature were reviewed. Results After three cycles of neoadjuvant chemotherapy, the postoperative pathological result after surgery suggested pathological complete remission （pCR）. Conclusion Neoadjuvant chemotherapy is effective for the treatment of patients with advanced colorectal cancer, and it is suitable for patients with advanced colorectal cancer before operation.