治疗痛风药物非布司他的临床应用与进展

为了更全面地了解治疗痛风新药非布司他（Febuxostat）的研发、临床应用信息,促进安全、合理用药,作者通过查阅大量的国内外文献,对非布司他基本情况、各国上市的时间、临床研究、安全性评价、注意事项等进行总结分析。非布司他作为新开发出来的治疗痛风的可选药物,疗效可靠,安全性较好,值得临床推广应用;作为新药,也应加强上市后的安全性监测。

Clinical Application and Progress in the Treatment of Gout Medication,Febuxostat

In order to fully understand the research and development of gout drug febuxostat and its clinical application, and improve safe and rational drug use, we have reviewed the progress and clinical application of Febuxostat. We have accessed to a large number of domestic and foreign literatures and summarized the febuxostat＇s basic situation, time-to-market and prices in different countries, clinical pharmacy, safety evaluation and precautions. Febu~ostat is a newly developed alternative drug for the treatment of gout and it has been proved effective, reliable and safe, which is worth clinical application. As a new product, the post-market medical safety monitoring is also necessary.