| 超声引导下微波消融治疗肾移植术后继发性甲状旁腺功能亢进 |
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| 引用本文： | 于明安,曹晓静,彭丽丽,魏莹,赵朕龙,尹琳,李妍.超声引导下微波消融治疗肾移植术后继发性甲状旁腺功能亢进[J].中国介入影像与治疗学,2020,17(3):133-136. |
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| 作者姓名： | 于明安 曹晓静 彭丽丽 魏莹 赵朕龙 尹琳 李妍 |
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| 作者单位： | 中日友好医院介入超声医学科, 北京 100029,中日友好医院介入超声医学科, 北京 100029,中日友好医院介入超声医学科, 北京 100029,中日友好医院介入超声医学科, 北京 100029,中日友好医院介入超声医学科, 北京 100029,中日友好医院介入超声医学科, 北京 100029,中日友好医院介入超声医学科, 北京 100029 |
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| 基金项目： | 首都临床特色应用研究项目（Z181100001718135）、北京化工大学-中日友好医院生物医学转化工程研究中心2018年度联合基金项目（PYBZ1804）。 |
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| 摘 要： | 目的评估超声引导下微波消融(MWA)治疗肾移植术后继发性甲状旁腺功能亢进(SHPT)的安全性和有效性。方法回顾性分析20例肾移植术后接受MWA治疗的SHPT患者,比较消融前后全段甲状旁腺激素(iPTH)、血钙、血磷、血肌酐和血尿素氮水平变化。结果20例患者共34枚甲状旁腺增生结节均一次性完全消融,平均最大径为(1.41±0.61)cm,中位消融时间219 s。消融后iPTH、血钙、血磷水平均明显低于消融前(P<0.05)。血肌酐、血尿素氮水平在消融前后无明显变化(P>0.05)。未见手术相关严重并发症发生。结论超声引导下MWA是治疗肾移植后SHPT安全、有效的方法。
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| 关 键 词： | 甲状旁腺功能亢进症 继发性 肾移植 超声检查 微波消融 |
| 收稿时间： | 2019/8/30 0:00:00 |
| 修稿时间： | 2020/2/7 0:00:00 |
Ultrasound-guided microwave ablation of secondary hyperparathyroidism after renal transplantation |
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| YU Ming''an,CAO Xiaojing,PENG Lili,WEI Ying,ZHAO Zhenlong,YIN Lin and LI Yan.Ultrasound-guided microwave ablation of secondary hyperparathyroidism after renal transplantation[J].Chinese Journal of Interventional Imaging and Therapy,2020,17(3):133-136. |
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| Authors: | YU Ming'an CAO Xiaojing PENG Lili WEI Ying ZHAO Zhenlong YIN Lin and LI Yan |
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| Institution: | Departmentof Interventional Ultrasound, China-Japan Friendship Hospital, Beijing 100029, China,Departmentof Interventional Ultrasound, China-Japan Friendship Hospital, Beijing 100029, China,Departmentof Interventional Ultrasound, China-Japan Friendship Hospital, Beijing 100029, China,Departmentof Interventional Ultrasound, China-Japan Friendship Hospital, Beijing 100029, China,Departmentof Interventional Ultrasound, China-Japan Friendship Hospital, Beijing 100029, China,Departmentof Interventional Ultrasound, China-Japan Friendship Hospital, Beijing 100029, China and Departmentof Interventional Ultrasound, China-Japan Friendship Hospital, Beijing 100029, China |
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| Abstract: | Objective To observe the safety and efficacy of ultrasound-guided microwave ablation (MWA) for treatment of patients with secondary hyperparathyroidism (SHPT) after renal transplantation (RT). Methods Data of 20 SHPT patients after RT who underwent MWA were retrospectively analyzed. The level of intact parathyroid hormone (iPTH), serum calcium, serum phosphorus, creatinine and blood urea nitrogen concentrations before and after MWA were assessed and compared. Results Complete ablation was achieved in a total of 34 parathyroid nodules among 20 SHPT patients. The mean maximum diameter of parathyroid nodule was (1.41±0.61)cm, and the median ablation time was 219 s. The mean iPTH, serum calcium and phosphorus concentrations after MWA were significantly lower than those before MWA (P<0.05). No significant difference of creatinine nor blood urea nitrogen was found before and after MWA (P>0.05). No major operation-related complication occurred in 20 patients. Conclusion Ultrasound-guided MWA is a safe and effective method for treating SHPT after RT. |
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| Keywords: | hyperparathyroidism secondary renal transplantation ultrasonography microwave ablation |
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