| 磁性药物载体在抗肿瘤方面的研究进展 |
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| 引用本文： | 马丽霞,余兰. 磁性药物载体在抗肿瘤方面的研究进展[J]. 药学研究, 2019, 38(4): 225-228 |
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| 作者姓名： | 马丽霞 余兰 |
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| 作者单位： | 兰州大学药学院，甘肃 兰州 730000,兰州大学药学院，甘肃 兰州 730000 |
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| 基金项目： | 国家自然科学基金资助项目（No.51501080）；兰州大学中央高校基本科研业务费专项资金资助（No.lzujbky-2018-134） |
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| 摘 要： | 通过外加磁场的引导作用，使负载抗癌药物的磁性载体靶向定位于靶区，提高靶组织的药物浓度，有效降低药物对正常组织或细胞的毒副作用及其他不良反应。磁性药物载体还具有靶向性、缓释、控释等优点，已成为了肿瘤靶向治疗常用的新型载体系统。本文综述了磁性药物载体磁性纳米颗粒、磁性脂质体、磁性微球在肿瘤治疗与诊断中的应用进展。
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| 关 键 词： | 靶向给药系统；磁性纳米颗粒；磁性脂质体；磁性微球 |
Research progress of magnetic drug carriers in antitumor |
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| MA Lixia and YU Lan. Research progress of magnetic drug carriers in antitumor[J]. Journal of Pharmaceutical Research, 2019, 38(4): 225-228 |
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| Authors: | MA Lixia and YU Lan |
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| Affiliation: | School of Pharmacy,Lanzhou University,Lanzhou 730000,China and School of Pharmacy,Lanzhou University,Lanzhou 730000,China |
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| Abstract: | The magnetic carrier carrying anticancer drugs is targeted to the target area by the action of external magnetic field, which increases the drug concentration of the target tissue and effectively reduces the toxic side effects.Magnetic drug carrier has the advantages of targeting, slow release and controlled release, and has become a new carrier system commonly used in tumor targeted therapy.This paper reviewed the application of magnetic drug carrier magnetic nanoparticles, magnetic liposomes and magnetic microspheres in the treatment and diagnosis of tumors. |
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| Keywords: | Targeted drug delivery system Magnetic nanoparticles Magnetic liposome Magnetic microspheres |
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