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清热药治疗糖尿病并发症的研究进展
引用本文:尹日凤,韦玥吟,谢晓琴,夏星,李宇清. 清热药治疗糖尿病并发症的研究进展[J]. 药学研究, 2018, 37(6): 352-355
作者姓名:尹日凤  韦玥吟  谢晓琴  夏星  李宇清
作者单位:1.广西中医药大学,广西高校中药药理重点实验室,广西 南宁 530200,1.广西中医药大学,广西高校中药药理重点实验室,广西 南宁 530200,1.广西中医药大学,广西高校中药药理重点实验室,广西 南宁 530200,2.广西中医药大学,广西壮瑶药重点实验室,广西 南宁 530200,1.广西中医药大学,广西高校中药药理重点实验室,广西 南宁 530200
基金项目:国家自然科学基金项目(No.NSFC81603525);广西自然科学基金项目(No.2015GXNSFAA139177);广西中医药大学研究生科研创新项目(No.YCSY2018048)
摘    要:
糖尿病患者机体在持续的高血糖状态影响下,常常发生多种糖尿病并发症,包括糖尿病肾病、糖尿病脑病、糖尿病心脏病、糖尿病眼病等,这些并发症已经成为糖尿病患者致死、致残的主要原因,中医药在治疗糖尿病并发症中发挥着重要的作用。中医药理论认为,热毒是糖尿病并发症发生的重要因素之一,主要是因糖尿病后期,脏腑功能低下,致气机及脏腑疏泄功能失调,引起浊瘀痰湿内蕴,日久而化热毒。针对此病机,中医在治疗糖尿病并发症时,多采取清热解毒的治疗方式,广泛应用清热类中药,因此,围绕近年来清热中药在治疗糖尿病并发症中的临床应用及基础研究作一综述。

关 键 词:糖尿病并发症;热毒;清热药

Research progress of heat-clearing drugs in treating diabetic complications
YIN Rifeng,WEI Yueyin,XIE Xiaoqin,XIA Xing and LI Yuqing. Research progress of heat-clearing drugs in treating diabetic complications[J]. Journal of Pharmaceutical Research, 2018, 37(6): 352-355
Authors:YIN Rifeng  WEI Yueyin  XIE Xiaoqin  XIA Xing  LI Yuqing
Affiliation:1.Guangxi University of Chingese Medicine,Key Laboratory of Pharmacology of Chinese Medicine, Nanning 530200,China;2.Guangxi University of Chingese Medicine,Zhuang Yao Medicine Laboratory of Guangxi, Nanning 530200,China,1.Guangxi University of Chingese Medicine,Key Laboratory of Pharmacology of Chinese Medicine, Nanning 530200,China;2.Guangxi University of Chingese Medicine,Zhuang Yao Medicine Laboratory of Guangxi, Nanning 530200,China,1.Guangxi University of Chingese Medicine,Key Laboratory of Pharmacology of Chinese Medicine, Nanning 530200,China;2.Guangxi University of Chingese Medicine,Zhuang Yao Medicine Laboratory of Guangxi, Nanning 530200,China,1.Guangxi University of Chingese Medicine,Key Laboratory of Pharmacology of Chinese Medicine, Nanning 530200,China;2.Guangxi University of Chingese Medicine,Zhuang Yao Medicine Laboratory of Guangxi, Nanning 530200,China and 1.Guangxi University of Chingese Medicine,Key Laboratory of Pharmacology of Chinese Medicine, Nanning 530200,China;2.Guangxi University of Chingese Medicine,Zhuang Yao Medicine Laboratory of Guangxi, Nanning 530200,China
Abstract:
Diabetic patients often suffer from various complications of diabetes, including diabetic nephropathy, diabetic encephalopathy,diabetic heart disease and diabetic ophthalmopathy under the influence of persistent hyperglycemia.These complications have become the leading cause of death and disability in diabetic patients, Chinese medicine plays an important role in the treatment of diabetic complications.Chinese medicine theory that heat toxicity is one of the important factors in the occurrence of diabetic complications,mainly because of late diabetes, organs dysfunction, qi organs and organs purging dysfunction,causing stasis phlegm dampness, as time goes by heat toxicity. In response to this pathogenesis,Chinese medicine in the treatment of diabetic complications,the treatment of detoxification to take more,widely used in traditional Chinese medicine,so this article around the heat in recent years,the treatment of diabetic complications in the clinical application and basic research to do a review.
Keywords:Diabetic complications  Heat toxicity  Heat-clearing medicine
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