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定量磁化率成像在帕金森病诊断、评估及手术方面的应用
引用本文:宋娟,李雨珊,吴曦.定量磁化率成像在帕金森病诊断、评估及手术方面的应用[J].中国临床医学,2020,27(4):693-696.
作者姓名:宋娟  李雨珊  吴曦
作者单位:海军军医大学基础医学院,上海,海军军医大学基础医学院,上海,海军军医大学附属长海医院神经外科,上海
基金项目:国家重点研发计划“数字诊疗装备研发”试点专项课题(2016YFC0105900)
摘    要:定量磁化率成像(quantitive susceptibility mapping, QSM)是现有磁共振序列中,评估帕金森病(PD)患者大脑区域铁积聚最灵敏的定量技术,在PD的鉴别诊断、病情评估、脑结构显像、外科治疗等方面都有明显优势。本文针对QSM在PD中的应用进行概述,以期帮助临床医师进一步了解和更好地应用该技术。

关 键 词:定量磁化率成像  磁共振成像  帕金森病  丘脑底核
收稿时间:2019/4/19 0:00:00
修稿时间:2019/8/21 0:00:00

Application of quantitative susceptibility mapping in diagnosis, evaluation and operation of Parkinson disease
SONG Juan,LI Yu-shan,WU Xi.Application of quantitative susceptibility mapping in diagnosis, evaluation and operation of Parkinson disease[J].Chinese Journal Of Clinical Medicine,2020,27(4):693-696.
Authors:SONG Juan  LI Yu-shan  WU Xi
Institution:School of Basic Medicine, Navy Military University, Shanghai, China,School of Basic Medicine, Navy Military University, Shanghai, China,Department of Neurosurgery, Changhai Hospital Affiliated to Navy Military University, Shanghai, China
Abstract:QSM is the most sensitive quantitative technique for evaluating the regional iron accumulation in brains of PD patients among the current magnetic resonance sequences, which has obvious advantages in the differential diagnosis of PD, evaluation of disease duration, brain structure imaging and surgical treatments, etc. This review summarizes the applications of QSM in diagnosis and treatment of PD, with a view to enable clinicians get further understandings and application of the technique.
Keywords:quantitive susceptibility mapping  magnetic resonance imaging  Parkinson disease  subthalamic nucleus  deep brain stimulation
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