| 一体化TOF-PET/MR的临床应用与挑战 |
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| 引用本文： | 阮伟伟,刘芳,孙逊,张永学,兰晓莉.一体化TOF-PET/MR的临床应用与挑战[J].中国医学影像技术,2018,34(12):1905-1908. |
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| 作者姓名： | 阮伟伟 刘芳 孙逊 张永学 兰晓莉 |
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| 作者单位： | 华中科技大学同济医学院附属协和医院核医学科, 湖北 武汉 430072;分子影像湖北省重点实验室, 湖北 武汉 430072,华中科技大学同济医学院附属协和医院核医学科, 湖北 武汉 430072;分子影像湖北省重点实验室, 湖北 武汉 430072,华中科技大学同济医学院附属协和医院核医学科, 湖北 武汉 430072;分子影像湖北省重点实验室, 湖北 武汉 430072,华中科技大学同济医学院附属协和医院核医学科, 湖北 武汉 430072;分子影像湖北省重点实验室, 湖北 武汉 430072,华中科技大学同济医学院附属协和医院核医学科, 湖北 武汉 430072;分子影像湖北省重点实验室, 湖北 武汉 430072 |
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| 基金项目： | 湖北省技术创新专项重大项目（2017ACA182）、华中科技大学同济医学院研究型临床医师资助计划（5001530008）。 |
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| 摘 要： | 精准化医疗是现代医学发展的趋势，而反映生命过程不同侧面信息的多模态影像学技术是实现精准化医疗的必要条件。PET及MRI的出现推动了多模态影像学的发展，特别是一体化TOF-PET/MR，可克服PET探测器与MRI强磁场相互干扰的技术难题、实现时间和空间上的同步扫描，对于从结构、功能、分子代谢等方面探索疾病的发生、发展及诊断具有重要意义。TOF技术有助于提高PET图像质量，降低假阳性或假阴性。本文就一体化TOF-PET/MR的临床应用及其面临的挑战进行综述。
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| 关 键 词： | 正电子发射体层摄影术 磁共振成像 一体化 |
| 收稿时间： | 2018/4/3 0:00:00 |
| 修稿时间： | 2018/9/11 0:00:00 |
Clinical application and challenge of integrative TOF-PET/MR |
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| RUAN Weiwei,LIU Fang,SUN Xun,ZHANG Yongxue and LAN Xiaoli.Clinical application and challenge of integrative TOF-PET/MR[J].Chinese Journal of Medical Imaging Technology,2018,34(12):1905-1908. |
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| Authors: | RUAN Weiwei LIU Fang SUN Xun ZHANG Yongxue and LAN Xiaoli |
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| Institution: | Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430072, China;Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430072, China,Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430072, China;Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430072, China,Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430072, China;Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430072, China,Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430072, China;Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430072, China and Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430072, China;Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430072, China |
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| Abstract: | Modern medicine is evolving toward precise medical treatment. Multi-modality imaging can comprehensively reflect different aspects of the life process, which is necessary for achieving precise medical treatment. PET/MR emerging will promote the development of multi-modality imaging, especially integrative TOF-PET/MR, which can overcome the technical difficulties of mutual interference between PET detectors and high magnetic fields in MRI, and realize synchronous scanning in time and space. It is of great significance for exploring the occurrence, development and diagnosis of diseases from many aspects, such as structure, function and molecular metabolism. TOF technique is helpful to improve the quality of PET images and reduce false positives or false negatives. The clinical application and challenge of TOF-PET/MR were reviewed in this article. |
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| Keywords: | Positron-emission tomography Magnetic resonance imaging Integrative |
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