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The characterization of the tidemark in human articular cartilage
Affiliation:1. Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs, Beijing, China;2. Clinical Pharmacology Research Center, Peking Union Medical College Hospital, State Key Laboratory of Complex Severe and Rare Diseases, NMPA Key Laboratory for Clinical Research and Evaluation of Drug, Beijing Key Laboratory of Clinical PK & PD Investigation for Innovative Drugs, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 41 Damucang Hutong, Xicheng District, Beijing 100032, China;1. Department of Orthopedics, Affiliated Hospital of Nantong University, Nantong 226001, People’s Republic of China;2. Department of Spine Surgery, The Second Affiliated Hospital of Nantong University, Nantong 226001, People’s Republic of China;3. Department of Immunology, Medical College, Nantong University, Nantong 226001, People’s Republic of China;4. Department of Pathogen Biology, Medical College, Nantong University, Nantong 226001, People’s Republic of China;5. Department of Medical Imaging, Medical College, Nantong University, Nantong 226001, People’s Republic of China;6. Department of Rheumatology, The Second Affiliated Hospital of Nantong University, Nantong 226001, People’s Republic of China;1. Clinical Research Centre, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China;2. Allergy and Clinical Immunology Research Centre, The First Affiliated Hospital of Liaoning Medical University, Jinzhou, Liaoning 121001, China;3. Department of Orthopaedics, Affiliated Hospital of Nanjing University of TCM, Nanjing, Jiangsu 210029, China;4. Central Laboratory of Suzhou Xiangcheng People’s Hospital, Suzhou, Jiangsu 215131, China
Abstract:
The tidemark has been characterized in fourteen human diarthrodial joints using histochemical and biochemical techniques. It stained selectively for lipid as well as for the enzymes alkaline phosphatase and ATPase. Preliminary biochemical data has shown a high concentration of calcium phospholipid phosphate complexes.
Keywords:
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