| 胆碱能药物在治疗阿尔茨海默病中的应用前景 |
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| 引用本文： | 王勇,张忠义,徐峰.胆碱能药物在治疗阿尔茨海默病中的应用前景[J].中国药业,2006,15(8):1-3. |
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| 作者姓名： | 王勇 张忠义 徐峰 |
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| 作者单位： | 南方医科大学珠江医院药学部,广东,广州,510282 |
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| 基金项目： | 国家自然科学基金;广东省自然科学基金 |
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| 摘 要： | 阿尔茨海默病（AD）是威胁老年人健康的重要疾病,但在治疗上尚无特效药物.当前临床治疗用药分为胆碱能药物、抗炎类药物、神经营养因子、激素类药物、抗氧化剂和神经保护剂,其中胆碱能类药物在缓解或阻止AD进一步恶化中占重要地位.该文简要介绍了不同种类的胆碱能药物在治疗AD中的应用与效果,并分析其应用潜能,以期为进一步开发更有效治疗AD的新药提供参考.
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| 关 键 词： | 阿尔茨海默病 胆碱能药物 治疗 |
| 文章编号： | 1006-4931(2006)08-0001-03 |
| 收稿时间： | 07 8 2005 12:00AM |
| 修稿时间： | 03 24 2006 12:00AM |
Prospect of Application of Cholinergic Drug in Alzheimer's Disease |
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| Wang Yong,Zhang Zhongyi,Xu Feng.Prospect of Application of Cholinergic Drug in Alzheimer''''s Disease[J].China Pharmaceuticals,2006,15(8):1-3. |
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| Authors: | Wang Yong Zhang Zhongyi Xu Feng |
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| Institution: | Department of Clinic Pharmacy, Zhujiang Hospital of the South Medical University, Guangzhou, Guangdong, China 510282 |
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| Abstract: | Alzheimer's disease(AD)represents one of the most common ailments afflicting the rapidly growing elderly segment of today's population.However,many evidences suggest the treatment does not provide benefits in patients with the disease.The drugs currently applied in clinic involve cholinergic drug,anti-inflammatory medications,neurotrophic factor,hormone antioxidant,and neuro-protective agent.Cholinergic drug is the most commonly used therapeutic agents in providing a significant delay or halt to disease progression.The primary aim of this article is to review application of cholinergic drug and to provide a direction for the effective treatment of AD through cholinergic drug. |
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| Keywords: | Alzheimer's disease cholinergic drug treatment |
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