| 诺维本、吡喃阿霉素联合治疗晚期乳腺癌 |
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| 引用本文： | 范玉华,于丁,邓华邦,柯玉华,蒋晖,付小玉,胡艳苹,杨玲,肖志华.诺维本、吡喃阿霉素联合治疗晚期乳腺癌[J].肿瘤防治研究,2000,27(6):470-471. |
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| 作者姓名： | 范玉华 于丁 邓华邦 柯玉华 蒋晖 付小玉 胡艳苹 杨玲 肖志华 |
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| 作者单位： | 430079,武汉,湖北省肿瘤医院 |
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| 摘 要： | 目的 观察诺维本 (NVB) +吡喃阿霉素 (THP)联合治疗晚期乳腺癌疗效。方法 NVB+THP联合治疗 31例晚期乳腺癌 ,均为女性 ,其中Ⅲ期 18例 ,Ⅳ期 13例。结果 本组 31例完全缓解 (CR) 3例 ,部分缓解 (PR) 16例 ,有效率为 61 3%。主要毒付反应 ,是骨髓抑制或静脉炎 ,白细胞下降为 93 2 %,其中Ⅲ、Ⅳ度为 50 2 %,静脉炎发生率为 4 2 0 %。结论 NVB +THP联合治疗乳腺癌 ,有效率较高 ,但骨髓抑制发生率高 ,必须引起重视。
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| 关 键 词： | 诺维本 吡喃阿霉素 晚期乳腺癌 药物疗法 |
| 收稿时间： | 2000-07-05; |
NVB and THP Combination Chemotherapy in the Treatment of Advanced Breast Cancer |
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| FAN Yu-hua,YU Ding,DENG Hua-bang,et al Hubei Cancer Hospital,Wuhan ,China.NVB and THP Combination Chemotherapy in the Treatment of Advanced Breast Cancer[J].Cancer Research on Prevention and Treatment,2000,27(6):470-471. |
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| Authors: | FAN Yu-hua YU Ding DENG Hua-bang Hubei Cancer Hospital Wuhan China |
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| Institution: | FAN Yu-hua,YU Ding,DENG Hua-bang,et al Hubei Cancer Hospital,Wuhan 430079,China |
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| Abstract: | Objective To evaluate the combined chemotherapy efficacy and toxicity of NVB and THP on advanced breast cancer.Methods All the 31 patients were treated with NT regimen NVB 25mg/M2 iv for Day 1 and 8;THP 45mg/m2 iv for Day 1.Results Complete response was 3 cases,Partial response 16 cases,the overall response rate was 61.3%. Side reactions were mainly myelosuppression and phlebitis.Conclusion The NT regimen is a better chemotherapy regimen for advanced breast cancer. |
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| Keywords: | s:NVB THP Chemotherapy Breast canc |
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