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| PCOS患者血清抗苗勒管激素(AMH)水平与胰岛素抵抗及雄激素的关系 | |
| 引用本文： | 肖琳,李启富,唐良萏. PCOS患者血清抗苗勒管激素(AMH)水平与胰岛素抵抗及雄激素的关系[J]. 生殖与避孕, 2011, 31(7): 488-490,494 |
| 作者姓名： | 肖琳 李启富 唐良萏 |
| 作者单位： | 1. 重庆医科大学附属第一医院妇产科,重庆,400016 2. 重庆医科大学附属第一医院内分泌科,重庆,400016 |
| 摘 要： | 目的:研究多囊卵巢综合征(PCOS)患者血清抗苗勒管激素(AMH)水平的变化及其与胰岛素抵抗(IR)和雄激素的关系。方法:回顾性分析85例PCOS患者及79例正常女性的体质量指数(BMI)、血清AMH、血糖、胰岛素、雄激素、稳态模型胰岛素抵抗指数(HOMA-IR)间的相互关系。血清AMH采用ELISA法测定,空腹血浆葡萄糖(FPG)采用葡萄糖氧化酶法测定,空腹胰岛素(FIns)采用化学发光法测定,睾酮(T)采用酶联免疫法测定。结果:PCOS组血清AMH水平明显高于对照组;Person相关分析表明,PCOS组血清AMH水平与HOMA-IR及BMI不相关,与雄激素、年龄相关。多元线性回归分析显示,PCOS组中血清雄激素水平是血清AMH的影响因素。结论:PCOS人群中血清AMH较正常女性升高,但其升高与IR无关,而与雄激素水平密切相关。 |
| 关 键 词： | 多囊卵巢综合征(PCOS) 抗苗勒管激素(AMH) 胰岛素抵抗(IR) 雄激素 |
Anti-Mullerian Hormone (AMH)Levels and its Relationships with Insulin Resistance and Androgen in Women with Polycystic Ovary Syndrome |
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| Lin XIAO,Qi-fu LIU,Liang-dan TANG. Anti-Mullerian Hormone (AMH)Levels and its Relationships with Insulin Resistance and Androgen in Women with Polycystic Ovary Syndrome[J]. Reproduction and Contraception, 2011, 31(7): 488-490,494 | |
| Authors: | Lin XIAO Qi-fu LIU Liang-dan TANG |
| Affiliation: | Lin XIAO1,Qi-fu LIU2,Liang-dan TANG1(1.Department of Gynecology and Obstetrics,the First Affiliated Hospital of Chongqing Medical University,Chongqing,400016)(2.Department of Endocrinology,400016) |
| Abstract: | Objective: To explore the relationships among insulin resistance(IR),androgens(T) and anti-Mullerian hormone(AMH) in women with polycystic ovary syndrome(PCOS).Methods: Eighty-five PCOS patients and 79 non-PCOS candidates were retrospectively analyzed.Body hight and weight were measured to calculate body mass index(BMI).BMI were calculated.AMH levels,fast blood glucose,fast blood insulin and androgen were assessed.Homeostatic model assessment of tissue insulin sensitivity(HOMA-IR) was calculated.The relatio... |
| Keywords: | polycystic ovary syndrome(PCOS) anti-Mullerian hormone(AMH) insulin resistance(IR) androgen |
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