MR-compatible pedal ergometer for reproducible exercising of the human calf muscle |
| |
| Affiliation: | 1. Medical Physics Group, Institute of Diagnostic and Interventional Radiology I, Jena University Hospital – Friedrich Schiller University Jena, Germany;2. Medical Engineering and Biotechnology, Jena University of Applied Sciences (EAH Jena), Germany;1. Department of Electronic Engineering, Fudan University, Shanghai 200433, China;2. Department of Electronic Science and Engineering, Nanjing University, Nanjing 211102, China;3. Department of Cardiovascular Surgery, West China Hospital, Sichuan University, 37 Guoxue Road, Chengdu, Sichuan 610041, China;4. Department of Thoracic and Cardiovascular Surgery, the Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, China;1. Department of Computer and Communication Engineering, National Kaohsiung First University of Science and Technology, Taiwan;2. Department of Electronics and Computer Science, Tung Fang Design Institute, Taiwan;1. Department of Physiology, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea;2. Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea;3. Department of Physiology, College of Medicine, Inje University, Busan 614-735, Republic of Korea;4. Division of Longevity and Biofunctional Medicine, Pusan National University School of Korean Medicine, Yangsan 626-870, Republic of Korea;1. Radboud University Medical Center, Orthopaedic Research Laboratory, Department of Orthopaedics, The Netherlands;2. University of Twente, Laboratory for Biomechanical Engineering, The Netherlands;3. Radboud University Medical Center, Spine Unit, Department of Orthopaedics, The Netherlands |
| |
| Abstract: | A pneumatic MR-compatible pedal ergometer was designed to perform dynamic contraction exercises of the human calf muscle in a whole-body 3 T MR scanner. The set-up includes sensors for monitoring mechanical parameters, such as pedal angle, cadence as well as applied force and power. Actual parameter values during the exercise were presented to the volunteer as a visual feedback to enable real-time self-adjustment of pedal deflection and cadence to the target reference value. Time-resolved dynamic 31P-MR spectroscopic measurements of phosphocreatine (PCr), inorganic phosphate (Pi) and pH were performed in a pilot experiment before, during, and after the exercise by a single volunteer. Two different load strengths were applied in these experiments (15% and 25% of the maximum voluntary contraction, MVC). As expected, mechanical and metabolic parameters differed for the two load levels. Small variations of the cadence, power and metabolic changes (time constants of PCr depletion and Pi accumulation) during the experiments demonstrate a highly reproducible mechanical output by the volunteer mediated by the ergometer. |
| |
| Keywords: | Ergometer Magnetic resonance spectroscopy Calf muscle |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
