Regioselective Glucuronidation of Oxyresveratrol,a Natural Hydroxystilbene,by Human Liver and Intestinal Microsomes and Recombinant UGTs |
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Affiliation: | 1. State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China;2. Department of Clinical Pharmacy, The First People''s Hospital of Changzhou, Changzhou, China;3. School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China;1. DMPK Research Laboratories Research Division, Mitsubishi Tanabe Pharma Corporation, Kisarazu, Japan;2. Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan;3. Tokyo University of Pharmacy and Life Sciences, Hachioji, Japan;4. Department of Pharmacy, Kyoto University Hospital, Kyoto, Japan;5. Kyoto Pharmaceutical University, Kyoto, Japan;6. Department of Membrane Biochemistry, Okayama University Graduate School of Medicine, Dentistry, & Pharmaceutical Sciences, Okayama, Japan;7. Research Institute, Sekisui Medical Company, Ltd., Ibaraki, Japan;8. Development Division, Mitsubishi Tanabe Pharma Corporation, Tokyo, Japan;1. Center for Drug Discovery, Baylor College of Medicine, Houston, TX 77030, USA;2. Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA;3. NMR and Drug Metabolism Core, Advanced Technology Cores, Baylor College of Medicine, Houston, TX 77030, USA;4. Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX 77030, USA;5. Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX 77030, USA;6. Center for Cell and Gene Therapy, Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX 77030, USA;7. Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA;8. Jan and Dan Duncan Neurological Research Institute, Texas Children''s Hospital, Houston, TX 77030, USA |
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