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涤痰化瘀汤防治急性脑卒中后抑郁的临床研究
引用本文:黄侃,陈眉,裘涛,张伟骏. 涤痰化瘀汤防治急性脑卒中后抑郁的临床研究[J]. 上海中医药杂志, 2011, 0(11): 51-53,59
作者姓名:黄侃  陈眉  裘涛  张伟骏
作者单位:上海交通大学附属第六人民医院中医科;浙江省中医院神经内科;
基金项目:浙江省中医药科技计划资助项目(2005A026)
摘    要:
目的观察涤痰化瘀汤防治急性脑卒中后抑郁(PSD)的作用。方法将102例急性脑卒中患者随机分为干预组(62例)及对照组(40例)。所有患者均采用常规脑卒中处理,干预组在常规治疗基础上加用涤痰化瘀汤。采用汉密尔顿抑郁量表(HAMD-17)评价抑郁状态发生率及变化,美国国立卫生研究院卒中量表(NIHSS)评价神经功能缺损改变。结果中药干预组较对照组PSD发生率降低,其中干预1个月组在3个月时发生抑郁比例明显低于对照组(P〈0.05);各随访时点,HAMD、NIHSS评分干预组较对照组均改善,而干预1个月组差异更显著(P〈0.05,P〈0.01),且在3个月时各方面均优于干预2周组(P〈0.05,P〈0.01)。结论涤痰化瘀汤早期干预可降低PSD发生,并能改善患者神经功能缺损。

关 键 词:脑卒中  抑郁症  涤痰化瘀汤  中医药疗法

Clinical research on Ditan Huayu Decoction in preventing and treating post-stroke depression
HUANG Kan,CHEN Mei,QIU Tao,ZHANG Wei-jun. Clinical research on Ditan Huayu Decoction in preventing and treating post-stroke depression[J]. Shanghai Journal of Traditional Chinese Medicine, 2011, 0(11): 51-53,59
Authors:HUANG Kan  CHEN Mei  QIU Tao  ZHANG Wei-jun
Affiliation:HUANG Kan1,CHEN Mei2,QIU Tao2,ZHANG Wei-jun2 1.The Sixth People's Hospital Affiliated to Shanghai Jiaotong University,Shanghai 2.Zhejiang Provincial Hospital of Traditional Chinese Medicine
Abstract:
Objective To observe the effects of Ditan Huayu Decoction in preventing and treating post-stroke depression(PSD).Methods One hundred and two patients were randomly divided into two groups.Sixty-two patients in treatment group were treated with Chinese medicine combined with routine therapy and forty patients in control group were treated with routine therapy only.The depression disorder and clinical neurological deficits were assessed by Hamilton Depression Rating Scale(HAMD-17) and National Institutes of H...
Keywords:Acute stroke  post-stroke depression  Ditan Huayu Decoction  Chinese medicine  
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