| 131I标记物介入治疗肝癌的临床研究进展 |
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| 引用本文： | 吴少平,卢武胜.131I标记物介入治疗肝癌的临床研究进展[J].中国普外基础与临床杂志,2003,10(5):513-515. |
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| 作者姓名： | 吴少平 卢武胜 |
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| 作者单位： | 四川大学华西医院肿瘤放疗科,成都,610041 |
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| 摘 要： | 目的 探讨^131I标记物介入治疗原发性肝癌的临床价值。方法 复习相关文献．并作综述性报道。结果 ^131I碘化油(^131I-LPD)及^131I免疫生物制剂均能较好地聚集于肝癌组织，适应证较广，严重的不良反应少见，近期疗效肯定，部分临床试验证实治疗后患者的生存率有提高。结论 运用^131I标记物介入治疗肝癌具有较好的临床应用前景。
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| 关 键 词： | ^131I标记物 介入治疗 肝癌 经肝动脉化疗栓塞 载体 |
| 文章编号： | 1007-9424(2003)05-0513-03 |
| 修稿时间： | 2002年3月11日 |
Clinical Study of Internal Radiotherapy with Hepatic Intra-arterial Iodine-131 Labeled Material for Hepatocellular Carcinoma |
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| WU Shao-ping,LU Wu-sheng.Clinical Study of Internal Radiotherapy with Hepatic Intra-arterial Iodine-131 Labeled Material for Hepatocellular Carcinoma[J].Chinese Journal of Bases and Clinics In General Surgery,2003,10(5):513-515. |
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| Authors: | WU Shao-ping LU Wu-sheng |
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| Institution: | WU Shao-ping,LU Wu-sheng. Department of Radiotherapy,West China Hospital,Sichuan University,Chengdu 610041,China |
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| Abstract: | Objective To discuss the clinical val ue of internal radiation therapy with hepatic intra-arterial iodine-131 labele d material for the treatment of hepatocellular carcinoma (HCC). Methods This summarized paper was made on literatu re review. Results Iodine-131-lipiodol and several reported iodine-131-labeled antibodies to HCC associated antigens were concentrated in the foci of HCC with a high tumor-to-normal-tissue absorbed dose ratios. No s evere side effects occurred. It was used in various kinds of HCC patients, and m ostly showed a significant tumor response. Survival rate of HCC patients was rai sed in several clinical trials.Conclusion Internal radiotherapy with hepatic intr a-arterial iodine-131 labeled material may be considered as an effective metho d to treat HCC. |
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| Keywords: | Iodine-131 Hepatocellular carci noma Chemoembolization Internal radiation therapy |
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