32例婴儿肝炎综合征临床分析

[目的 ]探讨婴儿肝炎综合征的病因、临床表现及预后 .[方法 ]对确诊为婴儿肝炎综合征的 32例病例资料进行临床观察及随访分析 .[结果 ]病原学检查结果提示病毒感染 ,尤其巨细胞包涵体病毒感染最多见 ,占 5 9% ,乙型肝炎病毒感染占第二位 ,为 2 5 % ;巨细胞包涵体病毒感染可引起黄疸、肝肿大、肝功能异常以及胆道闭锁、溶血 ,且病情重 ,易致肝硬化 ,日后有可能引起智能及听力障碍等后遗症 .[结论 ]巨细胞包涵体病毒感染是婴儿肝炎综合征的主要病因 ,早发现、早诊断及早治疗是避免发展成为肝硬化、降低死亡率和减轻后遗症的关键 .

Clinical analysis of 32 cases with infant hepatitis syndrome

OBJECTIVETo discuss the relations betwee n the cause of infant hepatitis syndrome and clinical manifestation and prognosis. METHODS32 cases with infant hepatitis syndrome were clinical ly analyzed and follow-up survey was carried out.RESULTSVir u s infection, especially cytomegalovirus infection(59%) played a key role and s econd infection of hepatitis B virus was 25%. The manifestations caused by cyto megalovirus were jaundice, abnormality of hepatic c ell function, occlusion of biliary tract, hemolysis, cirrhosis and complications of mental retardation and hearing handicap.CONCLUSIONMost o f hepatitis syndrome was caused by cytomegalovirus, and early diagnosis and trea tmen t are helpful in decreasing the mortality, preventing hepatic cirrhosis and less ening sequelae.