| 热放化疗对中晚期大肠癌癌组织中纤维连接素的影响及临床意义 |
| |
| 引用本文： | 赵东辉,周正端,齐德林,黄祥成. 热放化疗对中晚期大肠癌癌组织中纤维连接素的影响及临床意义[J]. 南方医科大学学报, 1994, 0(1) |
| |
| 作者姓名： | 赵东辉 周正端 齐德林 黄祥成 |
| |
| 作者单位： | 南方医院普外科 |
| |
| 摘 要： | 采用免疫组织化学方法证明：纤维连接素（Ｆｎ）在正常大陆组织中呈现规律性分布，大肠癌癌组织中Ｆｎ的含量减少。经热放化治疗的大肠癌病例，Ｆｎ在癌组织中的基膜、癌细胞间的结缔组织、肿瘤血管、肿瘤周围的结缔组织和肌组织中均明显增为；部分病例的肿瘤周围组织中Ｆｎ形成“带状屏障”。这提示癌细胞退变，淋巴细胞、炎细胞浸润及纤维组织增生与Ｆｎ的分布和含量变化有密切关系。
|
| 关 键 词： | 纤维连接素，大肠，肿瘤，热疗，放疗，化疗 |
Fibronectin in colorectal carcinoma after thermo-radio-Chemotherapy(TRC)and its clinical significance |
| |
| Zhao Donghui,Zhou Zhengduan,Qi Delin,et al. Fibronectin in colorectal carcinoma after thermo-radio-Chemotherapy(TRC)and its clinical significance[J]. Journal of Southern Medical University, 1994, 0(1) |
| |
| Authors: | Zhao Donghui Zhou Zhengduan Qi Delin et al |
| |
| Affiliation: | Zhao Donghui,Zhou Zhengduan,Qi Delin,et al Department of General Surgery,Nanfang Hospital |
| |
| Abstract: | By immunohistochemical method we have testified that fibronectin has a regular distribution in the normal large intestine;while inthe colorectal carcinoma,fibronectin content was less than in the normal tissue.In colorectal carcinoma treated with TRC fibronectinincreased obviously and its distribution changed. It was shown that distribution and content of fibronectin was closely related to of thecancer cells degeneratton, inflammatory infiltration and fibrosis |
| |
| Keywords: | fibronectin large intestine cancer thermo-radio-chemotherapy |
| 本文献已被 CNKI 等数据库收录！ |
