自体造血干细胞移植治疗侵袭性NK/T细胞淋巴瘤

目的 探讨自体造血干细胞移植(autologous hematopoietic stem cell transplantation,auto-HSCT)治疗侵袭性NK/T细胞淋巴瘤的疗效.方法 对我科2005年1月16日收治的1例侵袭性NK/T细胞淋巴瘤患者的造血干细胞移植和随访资料进行回顾性分析,并复习国内外相关文献...

Aggressive NK/T Lymphoma with Autologous Hematopoietic Stem Cell Transplantation

Objective To explore the therapeutic effect of autologous hematopoietic stem cell transplantation（auto-HSCT） on aggressive NK/T lymphoma.Methods The clinical data of one patient with aggressive NK/T lymphoma diagnosed in January 2005 were retrospectively analyzed,and the relevant domestic literatures were analyzed.Results This thirty-seven-year-old female patient had good disease control after undergoing chemotherapy with CHOAP and ICE regimens,surgery,and locoregional radiotherapy.After that,she had been collected enough bone marrow-derived hematopoietic stem cells,then underwent auto-HSCT with these cells.The conditioning regimen was TBI plus ECy.On the ＋29th day after transplantation,the hematopoietic reconstruction was successful.During the follow-up period,the patient was in complete remission status all along and her disease-free survival（DFS） was 67 months.Conclusion Auto-HSCT is effective on aggressive NK/T lymphoma.