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Artifactual hypocalcaemia after intravenous administration of gadodiamide (Omniscan).
Authors:Marc Decupere  Vanessa Ooms  Raymond Oyen  Dirk R J Kuypers  Kathleen Claes
Affiliation:Department of Nephrology andRenal TransplantationUniversity HospitalsLeuvenBelgiumEmail: Kathleen.Claes@uz.kuleuven.ac.be
Abstract:
Sir, It has been documented that certain gadolinium-based magneticresonance contrast agents injected for enhancement of magneticresonance imaging (MRI) or for angiography in selected patients,i.e. gadodiamide (Omniscan®) and gadoversetamide (Optimark®),can cause spurious hypocalcaemia, due to interference with colorimetricassays in a dose-dependent way [1–4]. Three other agentsapproved for clinical use, gadopentetate
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