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低剂量沙利度胺治疗多发性骨髓瘤的疗效分析
引用本文:赵卫平. 低剂量沙利度胺治疗多发性骨髓瘤的疗效分析[J]. 临床医学, 2010, 30(10): 6-7
作者姓名:赵卫平
作者单位:山东省菏泽市立医院血液科,菏泽,274030
摘    要:目的观察低剂量沙利度胺联合化疗治疗多发性骨髓瘤(MM)的疗效及不良反应。方法分析22例初治和8例复发难治MM患者应用低剂量沙利度胺联合化疗治疗的总有效率和不良反应;分析治疗前后患者M蛋白量、骨髓浆细胞比例以及血红蛋白浓度变化情况。结果 30例MM,完全缓解7例,部分缓解7例,微小反应4例,总有效率60%。治疗前后患者M蛋白量、骨髓浆细胞比例以及血红蛋白浓度相比差异有统计学意义(P〈0.05)。应用沙利度胺不良反应轻,均可耐受。结论低剂量沙利度胺联合化疗治疗多发性骨髓瘤安全有效。

关 键 词:多发性骨髓瘤  沙利度胺  联合

Analysis of curative effects on multiple myeloma using low dose of thalidomide and chemotherapy
ZHAO Weiping. Analysis of curative effects on multiple myeloma using low dose of thalidomide and chemotherapy[J]. Clinical Medicine, 2010, 30(10): 6-7
Authors:ZHAO Weiping
Affiliation:ZHAO Weiping.Department of Hematolgy,the Municipal Hospital of Heze,Heze 274030,China
Abstract:Objective To study the curative effects and adverse effects of the thalidomide combined with chemotherapy in treating multiple myeloma(MM).Methods Twenty-two patients were initially diagnosised as MM and 8 patients were refractory and relapsed MM who were used low dose of thalidomide combined with chemotherapy.Complete response(CR),partial response(PR),minimal response(MR) and adverse effects were observed.Changes of M-protein in serum,percentage of plasma cells in bone marrow and the level of hemoglobin we...
Keywords:Multiple myeloma  Thalidomide  Combination  
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