| 川芎嗪对大鼠局部脑缺血星形胶质细胞的影响 |
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| 引用本文： | 邵小鹏,刘勇.川芎嗪对大鼠局部脑缺血星形胶质细胞的影响[J].中国交通医学杂志,2001,15(4):362-364. |
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| 作者姓名： | 邵小鹏 刘勇 |
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| 作者单位： | [1]无锡市第三人民院214041 [2]西安交通大学医学院710061 |
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| 摘 要： | 目的 :观察川芎嗪对缺血后神经元改变和星形胶质细胞GFAP表达的影响。方法 :制作大鼠单侧局灶性脑缺血模型 ,HE染色观察神经元的形态学改变 ,免疫组化染色观察星形胶质细胞GFAP表达的变化。结果 :川芎嗪可提高星形胶质细胞GFAP表达。结论 :川芎嗪对缺血神经元有保护作用
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| 关 键 词： | 神经元 星形胶质细胞 川芎嗪 脑缺血 大鼠 |
EFFECT OF LIG ON THE CHANGE OF NEURONS AND ASTROCYTES AFTER FOCAL CEREBRAL ISCHEMIA IN RATS |
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| Shao Xiao-peng,WuXi No. People's Hospital ,Liu Yong,Medical School of Xi'an communication university.EFFECT OF LIG ON THE CHANGE OF NEURONS AND ASTROCYTES AFTER FOCAL CEREBRAL ISCHEMIA IN RATS[J].Chinese Medical JOurnal of Communications,2001,15(4):362-364. |
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| Authors: | Shao Xiao-peng WuXi No People's Hospital Liu Yong Medical School of Xi'an communication university |
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| Institution: | Shao Xiao-peng,WuXi No.3 People's Hospital 214041,Liu Yong,Medical School of Xi'an communication university 710061 |
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| Abstract: | Objective:To observe the effect of Lig pretreatment on the change of neurous and GFAP expression of Astrocytes after cerebral ischemia.Methods:MCAO was created in rat.focal ischemia in the rat cortex was induced by permanent occusion of the middle cerebral artery.The morphological change of neuron was observed using HE staining,the change of GFAP expression in Astrocyte was showed using immune cytochemistry method.Results:Lig can promote the expression of GFAP in astrocytes.Conclusions:Lig may serve the protective function for neuron survival. |
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| Keywords: | Neuron Astrocyte Lig Cerebral ischemia Rat |
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