体脂对DXA骨密度测量结果及骨质疏松诊断的影响

随着社会老龄化和生活水平提高，制约老年人健康长寿的骨质疏松症受到越来越多的重视。双能Ｘ线吸收测量法(dual energy X-ray absorptiometer，DXA)测量骨密度是诊断骨质疏松的金标准，但它的精确性受身体脂肪含量的影响。体脂可以干扰DXA测量骨密度的结果，这可能会导致体脂分布改变显著者（如绝经后体脂分布变化较大的女性）骨质疏松诊断的偏倚，造成此类人群骨质疏松时误诊或漏诊的发生。本文就脂肪对骨密度测量结果及骨质疏松诊断的影响作一综述。

Effect of body fat on the results of bone mineral density examination and osteoporosis diagnosis by DAX

With the aging of society and the improvement of living condition, more and more people were subjected to osteoporosis(OP).The diagnosis of OP is dependent on bone mineral density(BMD) measured by dual energy X-ray absorptiometer(DXA) which is used as a golden standard. But the body fat could interfere the measurement of BMD by DXA.So, to the people who had great changed body-fat such as the weight-gain women after menopause,the changed body-fat would impact the measured BMD value, and even result in unexpected consequences in their diagnosis of the osteoporosis: misdiagnosis and missed diagnosis. In this article, we will review the effect of body fat on the result of bone mineral density examination and the osteoporosis diagnosis by DAX.