Milestones in neuroimaging |
| |
| Authors: | A. Jon Stoessl CM MD FRCPC David J. Brooks MD DSc FRCP FMedSci David Eidelberg MD |
| |
| Affiliation: | 1. Pacific Parkinson's Research Centre, University of British Columbia & Vancouver Coastal Health, Vancouver, British Columbia, Canada;2. Centre for Neuroscience, Department of Medicine, Imperial College, Hammersmith Hospital, London, United Kingdom;3. Center for Neurosciences, Feinstein Institute for Medical Research, Manhasset, New York, USA |
| |
| Abstract: | ![]()
In the last 25 years there have been enormous advances in brain imaging. In addition to utility in diagnosis, these have led to novel insights into the pathogenesis of basal ganglia disease and the role of dopamine and the basal ganglia in normal health. The authors review highlights of this work, with a focus on advances in Parkinson's disease, the dystonias, Huntington's disease, and the role of dopamine in cognition and reward signaling. Emerging areas for future development include studies of functional connectivity, the analysis of default mode networks, studies of novel neurochemical pathways, methods to study disease pathogenesis, and the application of imaging techniques to investigate animal models of disease. © 2011 Movement Disorder Society |
| |
| Keywords: | Parkinson's dystonia Huntington disease dopamine positron emission tomography |
|
|
