美沙酮维持治疗人员与精神障碍的共病分析

目的:调查美沙酮维持治疗人员共病其他精神障碍情况。方法:采用DSM-Ⅳ-TR轴Ⅰ障碍定式临床检查(SCID-P)及人格障碍用定式临床检查手册(SCID-Ⅱ)调查100名美沙酮维持治疗人员精神障碍情况。结果:美沙酮维持治疗人员共患轴Ⅰ障碍主要是心境障碍(终生患病率26.0%)、焦虑障碍(终生患病率为23.0%)、其他活性物质所致精神障碍(11.0%);共患轴Ⅱ障碍主要是反社会人格障碍的比例最高(20.0%),其次是边缘性人格障碍(18.0%)、强迫性人格障碍(17.0%)。结论:美沙酮维持治疗人员中较多合并其他精神障碍,应积极关注共患疾病的诊断和治疗。

COMORBIDITY OF PSYCHIATRIC DISORDER IN INDIVIDUALS WITH METHADONE MAINTENANCE TREATMENT

Objective:To investigate the psychiatric comorbidity among individuals with methadone maintenance treatment.Methods: The Structured Clinical Interview for DSM-Ⅳ-TR-Patient Version(SCID-P) and the Structured Clinical Interview for DSM-Ⅳ-TR-axis II Personality Disorder(SCID-II) were used to assess current and lifetime DSM-Ⅳ-TR axis I diagnosis and the prevalence of DSM-Ⅳ-TR axis II personality disorder in 100 individuals with methadone maintenance treatment.Results: The lifetime prevalences of mood disorders,anxious disorders and other mental disorders caused by psychoactive substance were 26.0%,23.0%,and 11.0% among individuals with methadone maintenance treatment respectively.Among the axis II disorders,the prevalence of antisocial personality disorder,borderline personality disorder and compulsive personality disorder were 20.0%,18.0%,and 17.0% respectively.Conclusion: These findings suggest the prevalence of disorders of both axis Ⅰ and axis II in personnel receiving methadone maintenance treatment were high.It is necessary to focus on the diagnosis and treatment of psychiatric disorders comorbidities among heroin abusers receiving MMT.