| 壳聚糖与硫酸软骨素共混膜性质的研究 |
| |
| 引用本文： | 曹鹏,刘万顺,韩宝芹,陈列欢.壳聚糖与硫酸软骨素共混膜性质的研究[J].中国生物医学工程学报,2005,24(1):43-49. |
| |
| 作者姓名： | 曹鹏 刘万顺 韩宝芹 陈列欢 |
| |
| 作者单位： | 中国海洋大学海洋生命学院,青岛,266003 |
| |
| 基金项目： | 国家“十五”863课题资助项目 (2 0 0 1AA62 5 0 5 0 )，国家自然科学基金资助项目(3 0 0 70 2 2 0 )。 |
| |
| 摘 要： | 以壳聚糖和硫酸软骨素按一定比例制备出共混膜，研究了膜片的透光性、含水量、渗透性、力学性质、表面结构、生物降解性、生物相容性等性质。结果表明该共混膜具有较好的透光性、通透性、生物降解性和生物相容性，膜表面较粗糙。以此共混膜为载体培养兔角膜基质细胞，发现细胞在此共混膜上生长良好。制备膜片随着加入CaSO4量的增加，膜的通透性也随之增加。
|
| 关 键 词： | 壳聚糖 硫酸软骨素 共混膜 性质 生物降解 细胞培养 |
| 文章编号： | 0258-8021(2005)01-43-07 |
| 修稿时间： | 2003年12月23 |
Studies on the Properties of Chitosan and Chondroitin Sulfate Blend Membrane |
| |
| Cao Peng,LIU Wan-shun,HAN Bao-qin,CHEN Lie-Huan.Studies on the Properties of Chitosan and Chondroitin Sulfate Blend Membrane[J].Chinese Journal of Biomedical Engineering,2005,24(1):43-49. |
| |
| Authors: | Cao Peng LIU Wan-shun HAN Bao-qin CHEN Lie-Huan |
| |
| Abstract: | The chitosan and chondroitin sulfate were mixed with definite proportion to oblaine the blend membrane.The transparency,mechanical property,permeability,ultrastructure,adhesion,biodegradation and biocompatibility were studied.CaSO 4 powders were also added in blend membrane to increase the membrane permeability.Results showed that the blend membrane had rough surface and loosen structure,as well as better permeability,good transparency,biodegradation and biocompatibility.The results of culturing rabbit corneal keratocyte cells on the blend membrane showed that the blend membrane was compatible with corneal keratocyte cells.It was also found that the permeability was improved by blending CaSO\-4 powders into membrane,but the hygroscopicity was reduced. |
| |
| Keywords: | chitosan chondroitin sulfate blending membrane property biodegradation cell chulture |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
