Case-Control Study of the Risk Factors for Acquisition of Pseudomonas and Proteus Species during Tigecycline Therapy |
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Authors: | Ga Eun Park Cheol-In Kang Yu Mi Wi Jae-Hoon Ko Woo Joo Lee Ji Yong Lee Sun Young Cho Young Eun Ha Doo Ryeon Chung Kyong Ran Peck Jae-Hoon Song |
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Affiliation: | aDivision of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea;bDivision of Infectious Diseases, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, South Korea |
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Abstract: | Tigecycline is an important agent in clinical practice because of its broad-spectrum activity. However, it has no activity against Pseudomonas or Proteus species. We conducted a case-control study to analyze risk factors for the acquisition of Pseudomonas or Proteus spp. during tigecycline therapy. Placement of suction drainage at infected wound sites, ICU stay, and neurologic disease were identified as independent risk factors for the acquisition of Pseudomonas and Proteus spp. |
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