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Tracheal ulcer due to Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly
Institution:1. Department of Obstetrics and Gynecology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan;2. Department of Pathology, Faculty of Medicine, University of Yamanashi, Yamanashi, Japan
Abstract:A 74-year-old man was referred to our hospital because of a tracheal stenosis circumscribed with soft tissue density and a left pulmonary nodule. Open biopsy of a right submandibular lymph node revealed diffuse large B-cell lymphoma, and the malignant cells were positive for Epstein-Barr virus gene products. Bronchofiberscopy revealed a tracheal necrotizing ulcer. After chemotherapy, the tracheal ulcer resolved. To our knowledge, this is the first report of a case of Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly with a tracheal ulcer.
Keywords:Epstein-Barr virus  Lymphoma  Elderly  Tracheal ulcer  Bronchofiberscopy
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