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| 黄曲霉毒素诱发大鼠前胃肿瘤的观察 | |
| 引用本文： | 覃国忠,严瑞琪,覃柳亮,苏建家,黄国华. 黄曲霉毒素诱发大鼠前胃肿瘤的观察[J]. 广西医科大学学报, 1990, 0(4) |
| 作者姓名： | 覃国忠 严瑞琪 覃柳亮 苏建家 黄国华 |
| 作者单位： | 广西肿瘤防治研究所病理研究室，广西肿瘤防治研究所病理研究室，广西肿瘤防治研究所病理研究室，广西肿瘤防治研究所病理研究室，广西肿瘤防治研究所病理研究室 中山医科大学肿瘤中心 |
| 摘 要： | 本文报道用黄曲霉毒素(AFT)做长期诱癌实验,发现AFT除诱发肝细胞癌和骨肉瘤等恶性肿瘤外,同时诱发了41.30%(19/46)大鼠的前胃上皮增生和23.90%(11/46)的前胃乳头状瘤。结果表明,AFT对大鼠前胃有显著的致肿瘤作用。 |
| 关 键 词： | AFT 肝细胞癌 胃上皮增生 胃乳头状瘤 |
OBSERVATION OF FORESTOMACH NEOPLASIAS IN AFLATOXIN INDUCED RATS |
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| Affiliation: | Department of Pathology,Guangxi Cancer Institute Qin Guozhong,et al. |
| Abstract: | 100 male wistar rats were divided into control group and experimental group.The rats of the experimental group were injected intraperitoneally with aflatoxin(AFT),while those of the control group were given the same amount of DMSO only.Animals surviving through week 92 were killed for pathologic examination.Beside inducing hepatocellular carcinoma and osteosarcoma,AFT also induced epithelial hyperplasia (41.38%)and papilloma of the forestomach(23.38%)in the experimental group.The results showed that AFT can induce significant forestomach neoplasias in rats. |
| Keywords: | aflatoxin hepatocellular carcinoma forestomach neoplasm |
| 本文献已被 CNKI 等数据库收录！ | |