低强度氦-氖激光血管内照射对缺血性脑卒中患者血管内皮功能的影响

目的：探讨低强度氦－氖激光血管内照射疗法（ILLI）对缺血性脑卒中患者血管内皮功能的影响。方法：将48例缺血性脑卒中患者随机分为常规组和ILLI治疗组，ILLI治疗组在常规治疗组的基础上加用ILLI疗效。两组病人均于入院的次日及第29天应用高分辨率超声检测肱动脉流量介导的舒张活性（FMD）变化。结果：经四周的治疗后，两组的FMD值均较各自治疗前显著升高，但ILLI组的FMD升高较常规组更为显著。结论：低强度氦－氖激光血管内照射疗法能有效改善缺血性脑卒中患者的血管内皮功能。

Effects of intravascular low-level He-Ne laser irradiation therapy on vascular endothelial function in patients with ischemic stroke

Objective To explore the effects of intravascular low level He Ne irradiation(ILLI) therapy on vascular endothelial function in patients with ischemic stroke. Methods Fourty eight patients with ischemic stroke were randomly divided into ILLI therapy group and routine treatment group. Patients in the routine treatment group were treated with medications such as anticoagulants and calcium channel blocking agents, while those in the ILLI group were treated with ILLI therapy in addition to the routine treatment. Brachial artery flow mediated dilation(FMD) in all the patients was assessed by the high resolution ultrasonography in the 2nd and 29th day after hospitalization. Results FMD in either the ILLI group or the routine treatment group after four weeks of treatment was significantly greater than that before the treatment( P < 0.01 ), but the rise of FMD in ILLI therapy group was more obvious than that in the routine group. Conclusion Intravascular low level He Ne laser irradiation therapy can effectively improve vascular endothelial function in patients with ischemic stroke.