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深圳市无偿献血者丙型肝炎检测结果回顾性分析
引用本文:聂冬梅 王飞 尚桂芳 叶贤林 杨立新 周华. 深圳市无偿献血者丙型肝炎检测结果回顾性分析[J]. 江西医学检验, 2006, 24(2): 118-120
作者姓名:聂冬梅 王飞 尚桂芳 叶贤林 杨立新 周华
作者单位:广东省深圳市血液中心,518035
基金项目:深圳市科技局资助项目(编号:2005167)
摘    要:目的了解深圳无偿献血人群抗-HCV感染情况。方法对深圳市2000~2004年220218名无偿献血者血液标本抗-HCV ELISA试剂筛查阳性率进行分析比较,并对部分ELISA结果阳性的标本进行RIBA(重组免疫印迹试验)确认分析。结果深圳市无偿献血者HCV感染率呈逐年明显下降趋势(P〈0.005)。低于全国平均水平;抗-HCV ELISA试剂的存在一定的假阳性。结论应大力提倡无偿献血,提高检测试剂的特异性和灵敏度。进一步确保输血安全。

关 键 词:无偿献血 丙肝病毒 血液筛查 确认试验
文章编号:1008-0023(2006)02-0118-03

Retrospective analysis of the infectious status of hepatitis C virus of blood donors in Shenzhen
NIE Dongmei, WANG Fei, SHANG Guifang,et al.. Retrospective analysis of the infectious status of hepatitis C virus of blood donors in Shenzhen[J]. Jiangxi Journal of Medical Laboratory Sciences, 2006, 24(2): 118-120
Authors:NIE Dongmei   WANG Fei   SHANG Guifang  et al.
Affiliation:Shenzhen blood center ,Shenzhen 518035, China
Abstract:Objectivce To investigate the infectious status of hepatitis C virus(HCV) of blood donors in Shenzhen. Methods The positive rate of the antibody against HCV of 220218 blood donors detected by the enzyme-linked immunosorbent assay(ELISA), was analysed from 2000 to 2004. A part of positive samples were comfirmed by recobinant immunoblot assay(RIBA). Results The infectious rate of HCV was downtrend rapidly blood donors from 2000 to 2004 in Shenzhen and was lower than that of other part of china; false positive occasionally occurred using the reagent of the antibody against HCV by ELISA method. Conclusion It is necessary to advocate the voluntary blood donation and improve the specificity and sensitivity of the reagents for further blood safety.
Keywords:Voluntary blood donation   Hepatitis C virus   Blood screening   Confirmationof test
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