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红豆杉细胞的工业化培养
引用本文:吕晓辉,臧新,杨冬之.红豆杉细胞的工业化培养[J].时珍国医国药,2006,17(5):844-846.
作者姓名:吕晓辉  臧新  杨冬之
作者单位:郑州大学生物工程系,河南,郑州,450001
摘    要:介绍了近年来红豆杉细胞工业化培养生产紫杉醇的研究进展。重点介绍了添加诱导子、剪切力和溶解氧对紫杉醇产量的影响,以及利用生物反应器进行细胞培养时所存在的问题,为探索生产紫杉醇的最适条件和大规模细胞培养提供了理论依据。

关 键 词:红豆杉  紫杉醇  生物反应器
文章编号:1008-0805(2006)05-0844-02
收稿时间:2005-10-31
修稿时间:2006-02-20

The Cell Industrialization Culture of Taxus
L Xiao-hui,ZANG Xin,YANG Dong-zhi.The Cell Industrialization Culture of Taxus[J].Lishizhen Medicine and Materia Medica Research,2006,17(5):844-846.
Authors:L Xiao-hui  ZANG Xin  YANG Dong-zhi
Institution:L(U) Xiao-hui,ZANG Xin,YANG Dong-zhi
Abstract:The recent progress in the research on production of taxol by taxus cell industrialization culture was reviewed.Effects of addition of elicitors,shear stress and dissolved O_2 tension on taxol production and the problems in cell culture by using the bioreactor were reviewed emphatically.The theoretical envidence was provided for optimal conditions of producing taxol and cell culture in a large scale.
Keywords:Taxus chinensis  Taxol  Bioreactor
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