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Reference values for ultrasonograpy of peripheral nerves
Authors:Mohammad Qrimli MD  Hamid Ebadi MD  Ari Breiner MD  Hafsah Siddiqui MD  Majed Alabdali MD  Alon Abraham MD  Leif E. Lovblom  Bruce A. Perkins MD  Vera Bril MD
Affiliation:1. Ellen and Martin Prosserman Centre for Neuromuscular Diseases, Department of Medicine, Toronto General Hospital, University of Toronto University Health Network, Ontario, Canada;2. King Fahad Hospital, Ministry of Health, Madinah, Saudi Arabia;3. Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada;4. King Fahad University Hospital, University of Dammam, Dammam, Saudi Arabia;5. Division of Endocrinology and Metabolism, Department of Medicine, Mount Sinai Hospital and Lunenfeld–Tanenbaum Research Institute, University of Toronto, Toronto, Ontario, Canada
Abstract:Introduction: High‐resolution ultrasonography (HRU) is a novel method that provides morphological information about peripheral nerves. We aimed to determine reference values for nerve cross‐sectional area (CSA) on HRU. Methods: One hundred healthy volunteers had HRU of median, radial, ulnar, fibular, tibial, sural, and superficial fibular nerves at defined sites. The CSA was measured and the effects of age, gender, and body mass index (BMI) were evaluated. Results: CSA values in healthy subjects are described. CSA is larger in lower limb motor nerves than in sensory nerves at similar sites, and the CSA tends to be symmetrical. The strongest effect on CSA was for age, although gender and BMI had some effects. Conclusions: This study provides normative values for HRU, and it suggests that further research with age‐ and gender‐specific distributions must be a key priority in the development of HRU for use as a diagnostic test for peripheral nerve diseases. Muscle Nerve 53 : 538–544, 2016
Keywords:cross‐sectional area  neuropathy  peripheral nerve  reference values  ultrasound
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