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头颈部肿瘤涎腺放射性损伤的防治研究进展
引用本文:马婕,刘杨,罗宁斌,苏丹柯.头颈部肿瘤涎腺放射性损伤的防治研究进展[J].中华放射医学与防护杂志,2017,37(11):880-884.
作者姓名:马婕  刘杨  罗宁斌  苏丹柯
作者单位:530021 南宁, 广西医科大学附属肿瘤医院医学影像中心,530021 南宁, 广西医科大学附属肿瘤医院放疗科,530021 南宁, 广西医科大学附属肿瘤医院医学影像中心,530021 南宁, 广西医科大学附属肿瘤医院医学影像中心
基金项目:广西自然科学基金青年项目基金(2016GXNSFBA380211)
摘    要:放射性涎腺损伤是头颈部肿瘤患者放射治疗后最常见的并发症之一,表现为口腔疼痛,说话、吞咽困难等症状,严重影响患者的生存质量。因此,涎腺放射性损伤的防治十分重要。本文从放疗保护药物、放疗技术、分子生物学等方面,针对头颈部肿瘤涎腺放射性损伤的预防与治疗予以综述。

关 键 词:头颈部肿瘤  放射治疗  口干症/涎腺损伤  预防/治疗
收稿时间:2017/3/19 0:00:00

Recent progress in protecting salivary gland function after radiotherapy for patients with head and neck cancers
Ma Jie,Liu Yang,Luo Ningbin and Su Danke.Recent progress in protecting salivary gland function after radiotherapy for patients with head and neck cancers[J].Chinese Journal of Radiological Medicine and Protection,2017,37(11):880-884.
Authors:Ma Jie  Liu Yang  Luo Ningbin and Su Danke
Institution:Department of Radiology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China,Department of Radiation Oncology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China,Department of Radiology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China and Department of Radiology, Affiliated Tumor Hospital of Guangxi Medical University, Nanning 530021, China
Abstract:Radiation-induced salivary glands damage is one of the most frequent complications of head and neck cancers after radiation therapy. It leads to a series of symptoms which severely affect the quality of life, such as soreness of mouth, difficult talking, dysphagia and so on. Therefore, it is important to protect the function of salivary glands. In this review, relevant approaches to protecting the function of salivary glands after receiving the radiotherapy are discussed from several aspects,such as radioprotective drugs, radiotherapy technology molecular biology.
Keywords:Head and neck cancers  Radiotherapy  Xerostomia  Salivary gland dysfunction  Prevention  Therapy
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