甲状腺功能亢进性心脏病的超声心动图及相关因素分析

目的探讨甲状腺功能亢进性心脏病的超声心动图表现及相关危险因素。方法回顾分析361例甲亢患者(包括单纯甲亢及甲亢性心脏病患者)的超声心动图资料、一般临床资料及检测指标。结果单纯甲亢患者的左心室射血分数(LVEF)高于甲亢性心脏病(P<0.01),两组间左心房、左心室大小差异有统计学意义(P<0.05)。甲亢性心脏病组患者年龄、病程(P<0.01)、血清游离甲状腺素(FT4)水平、甲状腺体积及重量、收缩压和脉压差(P<0.05)均显著高于单纯甲亢组,血浆总胆固醇和三酰甘油均低于甲亢组(P<0.05)。结论年龄、病程及FT4水平是甲亢性心脏病的主要危险因素,超声心动图检查有助早期发现甲亢患者心脏结构和功能改变。

Analysis on echocardiograph features of hyperthyroid heart disease

Objective To discuss the echocardiographic features and risk factors of hyperthyroid heart disease.Methods Echocardiographic and clinical data of 361 patients with hyperthyroidism(including simple hyperthyroid patients and the patients with hyperthyroid heart disease) were retrospect analyzed.Results Ejection fraction of left ventricular(LVEF) in simple hyperthyroid patients were higher than that in patients with hyperthyroid heart disease(P<0.01).Left atrium and left ventricular cavity size had significant difference between the two groups(P<0.05).The age,course of disease(P<0.01),FT4,Thyroid volume and weight,systolic blood pressure and pulse pressure(P<0.05) were significantly increased in the patients with hyperthyroid heart disease.TC and TG were significantly lower in the patients with hyperthyroid heart disease compared with simple hyperthyroid patients(P<0.05).Conclusion Echocardiography can reflect hyperthyroid heart structure and function change,contributing to early diagnosis and clinical treatment of this disease.The larger age,longer course of disease,higher FT4 lerel are the major risk of hyperthyroid heart disease.