| 槐米化学成分研究Ⅱ |
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| 引用本文： | 刘丽丽,王涛,李晓霞,等.槐米化学成分研究Ⅱ[J].辽宁中医药大学学报,2014(7):51-53. |
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| 作者姓名： | 刘丽丽 王涛 李晓霞 等 |
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| 作者单位： | 天津市中药化学与分析重点实验室,天津300193 |
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| 基金项目： | 国家自然基金项目（81202995）; 国家科技重大专项项目-重大新药创制项目（2011ZX09307-002-01）; 新世纪优秀人才支持计划项目（NCET-12-1069） |
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| 摘 要： | 目的:对槐米(Sophora japonica L.)70%乙醇提取物化学成分进行研究,为进一步开发利用该植物资源提供依据。方法:采用正相硅胶、反相ODS、Sephadex LH-20等柱色谱及高效液相色谱法等手段进行分离纯化,并通过理化性质与光谱分析鉴定化合物的结构。结果:从槐米(Sophora japonica L.)70%乙醇提取物中分离鉴定了5个单体成分,分别为:(1)licoagroside B、(2)maltol 3-O-(4'-O-p-coumaroyl-6'-(3-hydroxy-3-methylglutaroyl))-β-glucopyranoside、(3)(E,E)-terrestribisamide、(4)N-p-coumaroylN'-feruloylputrescine、(5)(1'R,3'S,5'R,8'S,2Z,4E)-dihydrophaseic acid。结论:化合物1、3~5为首次从槐属植物中分离得到的化合物。
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| 关 键 词： | 槐米 化学成分 结构鉴定 |
Isolation and Identification of Chemical Constituents from Flos Sophorae II |
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| LIU Lili,WANG Tao,LI Xinaxia,SHI Pingping,LIU Erwei,ZHANG Yi.Isolation and Identification of Chemical Constituents from Flos Sophorae II[J].Journal of Liaoning University of Traditional Chinese Medicine,2014(7):51-53. |
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| Authors: | LIU Lili WANG Tao LI Xinaxia SHI Pingping LIU Erwei ZHANG Yi |
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| Institution: | ( Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China ) |
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| Abstract: | Objective ： To study the chemical constituents from 70% EtOH extract of Flos Sophorae. Methods ： The compounds were isolated by chromatographies, such as silica gel, ODS, Sephadex LH-20 and HPLC, and identified by the chemical and physical methods, especially spectral analysis. Results： Five constituents were isolated. The structures of them were identified as （ 1 ） licoagroside B, （ 2 ） mahol 3-0- （ 4＇-O-p-coumaroyl-6＇-O- （ 3-hydroxy-3-methylglutaroyl ） ） - β -glucopyranoside, （ 3 ） （ E, E ） -terrestribisamide, （ 4 ） N-p-coumaroyl-N＇-feruloylputreseine, （ 5 ） （ 1 ＇R, 3＇S, 5＇R, 8＇S, 2Z, 4E ） - dihydrophaseic acid. Conclusions ： Compounds 1 and 3,4,5 were isolated from Sophorae genus firstly. |
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| Keywords: | Flos Sophorae chemical constituents structure identification |
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