合并癫痫的低级别胶质瘤手术治疗效果分析

目的探讨合并癫痫的低级别胶质瘤手术治疗的效果,为合并癫痫的低级别胶质瘤患者提供一个恰当的手术方案。方法回顾性分析肿瘤切除程度、术中处理致痫灶的方式对患者癫痫控制程度的影响。结果两组肿瘤全切和次全切、部分切除在处理致痫灶与不处理致痫灶患者癫痫控制满意率比较,差异均有统计学意义(P<0.05)。单纯切除组肿瘤全切和次全切与部分切除后患者癫痫控制满意率比较,差异有统计学意义(P<0.01)。结论对于合并癫痫的低级别胶质瘤患者手术治疗,术中应尽量全切肿瘤,同时根据皮质脑电监测处理致痫灶。

Effect of Surgical Treatment on Low-grade Glioma Merged with Epilepsy

Objective To investigate the effect of surgical treatment on low-grade glioma merged with epilepsy and to provide a proper operation plan for the patients.Methods The seizure control of epilepsy among patients with different tumor resection extent and intraoperative treatment of epileptic foci was retrospectively analyzed.Results Between the two groups,the seizure control of epilepsy by total resection,subtotal resection or partial resection of epileptic foci was better than those without treatment.The difference was statistically significant(P<0.05).The seizure control of epilepsy between partial tumor resection and total tumor resection or subtotal tumor resection showed statistically significant difference(P<0.01).Conclusion In the surgery of low-grade glioma combined with epilepsy,tumor should be totally removed.Meanwhile,epileptic foci should be treated according to cortical EEG monitoring.